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ENGINEERED TO
STAY SHARP LONGER
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FOCUS:
150mg of GeniusPure® Alpha GPC to support memory, focus and alertness
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STAY CALM:
20mg of SalidroPure® (natural salidroside from the rhodiola rosea plant) to handle stress and remain calm on hard days.
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RECHARGE:
72 trace minerals to hydrate from the inside. We call this ConcenTrace®.
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OPTIMIZE:
2 mg of MaxCatalyst® (black pepper extract / piperine) to support better absorption of key ingredients.
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ENERGIZE:
500mg of vitamin C, 500mcg of vitamin B12, and 110mg of magnesium to keep your brain engaged.
Focus
SHOP NOW
A Word From Howie Mandel
Howie Mandel knows what it's like when your brain won't cooperate. After decades on stage, on set, and in front of the camera, he ditched the coffee crash for a stimulant-free formula built for the focus, mental clarity, and stress resilience the work actually demands.
Brain Fuel+ is the daily routine Howie uses to stay sharp — no jitters, no crash, just steady mental energy when life demands more.
Supports focus, speed, memory and attention
WHAT EXPERTS ARE SAYING
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Lucas Kaelin
Supplement and Review Expert - Texas US
As someone who has tested hundreds of formulas in this industry, Brain Fuel + Hydration from Lithios feels extremely intentional. I recently put it to the ultimate test by replacing my daily high caffeine intake with zero caffeine and using this f... As someone who has tested hundreds of formulas in this industry, Brain Fuel + Hydration from Lithios feels extremely intentional. I recently put it to the ultimate test by replacing my daily high caffeine intake with zero caffeine and using this formula instead. I experienced none of the withdrawal symptoms I would normally expect such as brain fog, drowsiness, or lack of motivation. The combination of GeniusPure® Alpha GPC, high potency SalidroPure®, ConcenTrace® Trace Minerals, MAXCatalyst™, and its foundational micronutrient support provided steady mental clarity, drive, and focus without the crash or dependency that often comes with stimulants. It supported real performance instead of simply stimulating it. Highly recommend! -
Dr. Darrin Starkey N.D.
Manager of Education and Training for Trace
We lose trace minerals every day—through respiration, perspiration, urination, and defecation—so you don’t need a gym membership to become dehydrated. You don’t have to be an athlete to hydrate like one, either. Even a gold-medal couch potato can ... We lose trace minerals every day—through respiration, perspiration, urination, and defecation—so you don’t need a gym membership to become dehydrated. You don’t have to be an athlete to hydrate like one, either. Even a gold-medal couch potato can level up when their water comes with a full-spectrum trace mineral upgrade. -
Yota N
Life & Health Coach, ICF.
As a life and health coach, I always emphasize that true performance comes from consistent daily habits. Lithios Brain Fuel supports hydration and essential nutrients that help create a strong foundation for clarity, resilience, and long-term cogn... As a life and health coach, I always emphasize that true performance comes from consistent daily habits. Lithios Brain Fuel supports hydration and essential nutrients that help create a strong foundation for clarity, resilience, and long-term cognitive wellness which helps with energy and sustainability. -
Alex G
Private Pilot, Toronto, Canada
I use Lithios Brain Fuel Plus Hydration Mix as part of my pre-flight routine, especially on longer legs. It gives me a noticeable improvement in focus and mental clarity. -
Dustin Elliot
Chief Branding Officer NNB Nutrition
NNB Nutrition has remained at the forefront of nutrition innovation for years, and Lithios Brain Fuel represents that market leading innovation utilizing pure salidrosides, which are typically found in tiny amounts in the adaptogen Rhodiola; as we... NNB Nutrition has remained at the forefront of nutrition innovation for years, and Lithios Brain Fuel represents that market leading innovation utilizing pure salidrosides, which are typically found in tiny amounts in the adaptogen Rhodiola; as well as the only choline ingredient showing benefits with a single dose. -
Karl Hollenbacher
Nutraceutical Manufacturing Executive
Lithios nailed it with Brain Fuel - a smart, well formulated blend that actually delivers on focus, cognition, and sustained mental energy.
FIND YOUR DAILY BRAIN FUEL
A stimulant-free + hydration drink mix designed for daily cognitive performance.
✓
2 Full-Size 30-day Brain Fuel Hydration Tubs (1 of each flavor).
Your 60-day cognitive performance kickstart.
✓
Premium Lithios Shaker.
Heavy-weight stainless mixer cup. The perfect sidekick for your morning ritual.
Cognition ·
Hydration ·
Stress Resilience·
Cellular Energy · memory ·
HOW BRAIN FUEL+
SUPPORTS COGNITIVE PERFORMANCE
1
HIgh Performers
You are required to perform at your best all the time: meetings, strategy sessions, analysis, team management.
Coffee and energy drinks stimulate your brain for a moment, but they're not sustainable.
Brain Fuel+ keeps you steady and sharp throughout the day, no crash, no jitters.
2
50+ Active Adults
You like living on your own terms, without depending on anyone or stop doing the activities you love.
You understand the importance of having a clear mind from dawn to dusk; while being able to act and decide on the spot. Brain Fuel+ supports your daily routine, adding nutrients to keep you stable and focused, without ups and downs.
What our customers say
Don't just take our word for it
real people. Real Results.
Frequently asked questions
What is Lithios Brain Fuel + Hydration?
Lithios Brain Fuel is a premium daily and focus formula designed to support mental clarity, cognitive performance, and sustained energy. Unlike most formulas that rely on stimulants, fillers, or minimal active ingredients, Lithios is built around what's actually happening in your brain underneath the surface. Our formula is powered by three signature performance components:
GeniusPure® Alpha-GPC — one of the most studied ingredients, supporting focus, learning, mental processing speed, and clarity without the jitters or crash.
SalidroPure® Adaptogen Extract — supports stress resilience and mental endurance, especially during long days when mental fatigue starts to set in.
MaxCatalyst®Fast Absorption — ensures every compound is delivered efficiently so your brain actually gets what it needs, when it needs it.
Rounded out with magnesium, vitamin B12, vitamin C, and 70+ trace minerals, Lithios provides clean, consistent cognitive support throughout the day — no stimulants, no fillers, no shortcuts. Just your brain functioning the way it was designed to.
What ingredients are in Lithios Brain Fuel+ and what does each one do?
Lithios Brain Fuel+ contains seven active ingredients, each chosen for a specific role in cognitive performance, hydration, and cellular energy. The formula is fully transparent — no proprietary blends.
Here is the complete active ingredient breakdown:
- Vitamin C — 500mg: Supports antioxidant defense and immune resilience, protecting brain cells from oxidative stress during high-demand periods
- Vitamin B12 (Methylcobalamin) — 500mcg: Supports nervous system function, energy metabolism, and the reduction of mental fatigue; methylcobalamin is the most bioavailable form of B12
- Magnesium (Citrate + Trace Mineral Blend) — 110mg: Supports muscle function, hydration balance, and neurological recovery — particularly important for people experiencing chronic stress
- ConcenTrace® Trace Minerals — 300mg: Delivers 72+ ionic trace minerals for electrolyte replenishment and cellular hydration; trace minerals are essential cofactors for vitamin absorption and fluid regulation
- GeniusPure® Alpha GPC — 150mg: A clinically studied, highly purified form of alpha-glycerylphosphorylcholine that drives acetylcholine production to support focus, processing speed, and cognitive clarity; in clinical testing, 350mg GeniusPure® demonstrated a 108% greater improvement in cognitive performance vs. placebo
- SalidroPure® — 20mg (98% salidroside): A concentrated adaptogen extract equivalent in salidroside content to approximately 2,000mg of standard Rhodiola rosea extract; supports HPA-axis regulation, stress resilience, and mental endurance without nervous system overstimulation
- MaxCatalyst® (Piperine System) — 2mg: A bioavailability-enhancing system clinically shown to improve absorption ensuring nutrients reach the cell, not just the bloodstream
What makes Lithios different from other focus products?
Many hydration or focus products rely on fillers, limited actives, or heavy stimulants. Lithios is built differently. We combine:
- GeniusPure® for mental clarity
- SalidroPure™ adaptogen extract for resilience and endurance
- 71+ essential trace minerals needed for daily body function and cellular hydration
- Magnesium for nerve and muscle function- supports 300 biochemical reactions in your body
- B12 for cognitive function and healthy nerve cells
- Vitamin C for powerful antioxidant, boost immunity
- Fast Absorption Technology for rapid uptake
Trace minerals are included because they are essential cofactors for virtually every biological process that supports cognitive function — including energy metabolism, neurotransmitter synthesis, and cellular hydration. Without adequate trace mineral levels, even high-quality vitamins cannot perform optimally.
Lithios uses ConcenTrace® Trace Minerals (300mg), which delivers 72+ ionic trace minerals in bioavailable form. Key functions include:
- Trace Minerals: Trace minerals regulate fluid movement in and out of cells, directly supporting cellular hydration and reducing the mental fatigue associated with even mild dehydration
- Vitamin cofactor activity: Minerals like magnesium, zinc, and selenium are required for B-vitamin activation, antioxidant enzyme function, and acetylcholine synthesis
- ATP energy production: Several trace minerals serve as cofactors in mitochondrial energy pathways, supporting the cellular energy that underlies sustained focus and mental output
As Dr. Darrin Starkey N.D., Manager of Education and Training for Trace, notes: trace minerals are lost daily through respiration, perspiration, and urination — consistent replenishment is foundational to daily performance.
When should I take Lithios Brain Fuel+ for the best results?
The best time to take Lithios Brain Fuel+ is before any mentally demanding activity — most commonly in the morning, before work or study sessions, or ahead of a workout. Because it contains no caffeine or stimulants, it can also be used in the afternoon without disrupting sleep. One scoop mixed with water is the standard daily serving, though some users take it twice daily.
The key ingredients explain why timing matters:
- GeniusPure® Alpha GPC (150mg) supports acetylcholine production and peak cognitive output — most effective when taken 30–60 minutes before demanding mental work
- SalidroPure® (20mg, 98% salidroside) supports stress adaptation and mental endurance throughout the day, making morning use ideal for sustained performance
- ConcenTrace® Trace Minerals (300mg, 72+ minerals) replenish electrolytes lost overnight, supporting cellular hydration from the start of your day
- MaxCatalyst® Piperine System (2mg) enhances absorption of all active ingredients, so consistent daily timing helps maximize bioavailability
Does it contain sugar or caffeine?
No. Lithios contains zero sugar, no stimulants, and no caffeine. Instead of relying on harsh energy spikes, it uses trace minerals and cognitive-support ingredients to deliver clean, steady performance.
Do you offer free shipping?
Yes. Brain fuel plus hydration orders over $100 automatically qualify for free shipping at checkout.
Where are your products manufactured?
Our products are manufactured in the USA at a FDA registered facility, NSF, GMP.